Kevin Smith has been blogging about his next movie, Zack and Miri Make a Porno for quite awhile, and he was finally able to reveal that the two leads will be Seth Rogen and Elizabeth Banks. Rogen is the Knocked Up guy and the stock room dude from The 40-Year-Old Virgin. Banks was the horny pervert in 40 but I think at this point I mostly think of her for being in Scrubs as the mother of J.D.'s child. (If you blinked, she was also JJJ's secretary in the Spiderman movies, wearing a black bob wig.)
Smith has said the movie is pretty much what the title indicates it is, so given that kind of comedy, it sounds like they'll be good for the flick. I'm excited for a new movie from Silent Bob.